18th Mentored Paper (Summer 2026)

Topics

MPI 18.1: Skeletal muscle angiogenesis in response to hypoxia, considering environmental and exercise conditions (literature review)

MPI 18.2: What is the role of histone modifications in mediating skeletal muscle adaptation to exercise (literature review)

MPI 18.3: What role do environmental triggers (such as viral infections, diet, or early-life microbiome changes) play in initiating autoimmune responses that lead to Type 1 diabetes?

MPI 18.4: How do failures in central or peripheral immune tolerance lead to the destruction of self-tissues in autoimmune diseases?

MPI 18.5: Can early biomarkers (genetic, immunological, or metabolic) reliably predict the development of Type 1 diabetes before clinical symptoms appear?

MPI 18.6: How do experiences of maternal health care differ between Indigenous and non-Indigenous women in Canada, and what are the implications for health outcomes and healthcare delivery?

MPI 18.7: How do marginalized youth in Canada navigate mental health barriers, and in what ways do cultural contexts and gender differences influence the accessibility of mental health services?

MPI 18.8: What are the similarities and differences in host immune activation between acute viral infections and chronic infections?

MPI 18.9: What are the key cytokine profiles that distinguish mild from severe COVID-19 infection?

MPI 18.10: What role do host transcription factors play in regulating viral gene expression across different viral families?

MPI 18.11: How does the expression of host-defense peptides (HDPs) differ between tissue types in animals?

MPI 18.12: How do secreted factors support innate immune defense in different mucous membranes (lung, gut, endometrium, etc.)?

MPI 18.13: Can Parkinson's disease be detected by smell?

MPI 18.14: How can we model plasticity?

MPI 18.15: What is the effect of the Earth's magnetic field on the human brain, if any?

MPI 18.16: To what extent will climate change uncouple trophic links due to phenological change? E.g. Timing of hibernation in the face of shifting seasonal food availability.

MPI 18.17: How do nutrients other than nitrogen and phosphorus affect (or limit) productivity in ecosystems?

MPI 18.18: What are the roles of RNA in DNA double-strand break repair pathways?

MPI 18.19 What are some of the possible biochemical mechanisms governing freeze tolerance in intertidal animals?

MPI 18.20 What drug delivery methods can be used to specifically target anti-inflammatory agents to the diseased tissue in patients with inflammatory bowel disease (IBD)? (Literature review)

MPI 18.21 How do the effectiveness and safety profiles of different classes of drugs (e.g. 5-aminosalicylates, steroids, biologics) vary in the treatment of Crohn’s Disease vs. ulcerative colitis? (Literature review)